Coronavirus is a viral fever that has been declared a pandemic by the World Health Organization (WHO). Coronavirus or COVID-19 is an infectious disease that has affected around 200 countries and territories of the world. Countries are now researching for a suitable coronavirus vaccine.
This disease has also affected two international conveyances: the Holland America’s MS Zaandam Cruise Ship and the Diamond Princess Cruise Ship Harbored in Yokohama, Japan. This disease is the result of a newly revealed virus called ‘coronavirus.’
Basic Defensive Ways against the Novel Coronavirus
Incase of coronavirus, prevention is always better than cure, at least for the time being. The main defensive ways to protect yourself and others from the Novel COVID-19 are:
- Wash Your Hands at Intervals
The foremost way is to wash your hands frequently. You must clean your hands with an alcohol-based sanitizer or with soap and water at intervals. It will kill viruses if present on your hands.
- Continue Social Distancing
Next, you must practice social distancing. Social distancing must be of at least 1 meter (3 feet) between you and anyone who is coughing or sneezing.
- Do not Touch Eyes, Nose, and Mouth
Generally, hands touch many surfaces and get contaminated. The dirty hands can transmit the virus to your eyes, nose, or mouth. You will fall sick when the COVID-19 virus enters your body. Therefore, you must avoid touching your face, eyes, nose, or mouth with dirty hands.
- Follow Respiratory Etiquette
All of us must follow good respiratory hygiene to protect others from viruses like flu, cold, and COVID-19. It means you must cover your mouth and nose with your flexed/bent elbow or tissue while coughing or sneezing. You must dispose of the used tissue immediately in a closed bin.
- If Sick Stay at Home
If you feel unwell, stay at your home, and wear a mask. You must avoid unnecessary travel or large public groups. This will help to keep away from this viral fever. If you feel COVID-19 symptoms, do not panic. Simply contact the nearest national or local health authorities without any delay. Avoid smoking as it declines lungs functioning.
- Get Medical Care Early if You Experience Fever, Cough, and Breathing Difficulty
In case you have a fever, cough, and shortness of breath, seek medical care by calling in advance. It is essential to abide by the directions of national or local health authorities. By attaining medical treatment early, this ailment can be cured.
It is important to disclose your contact with an infected person or past travel history (past 14 days) to any COVID-19 affected country/region to your medical care provider. It is significant to follow the guidelines of the Government to assist in fighting this disease.
Coronavirus Vaccine Update
Is there a vaccine for the coronavirus disease? At present, there is no identifiable coronavirus vaccine or treatments for novel coronavirus. However, various in-progress clinical trials are assessing potential treatments. There are many companies and medical research institutes which have claimed to have discovered that life-saving antidote, but neither of them is tested to that extent.
Note: Do not treat yourself by taking medicines without prescription if your sense COVID-19 symptoms.
Who are in the race to find out the vaccine?
At least 35 companies and academic institutions all over the world are in the race to create a possible coronavirus vaccine. Out of these four have been testing in animals. As per reports, Boston-based biotech firm Moderna will be the first to conduct human trials soon.
Coronavirus Vaccine Trials in the US
Chloroquine and Hydroxychloroquine are the two drugs that the United States FDA recognized as potential coronavirus treatments. This claim is on the basis of small and limited studies in human and lab tests. But medical trials show that these drugs are yet to reach full potential. It is more a preventive drug than a cure. in the US. So, it is certain that the FDA has not officially determined that these drugs help in fighting COVID-19.
New Update – COVID-19 Vaccines Trials That Failed
Hydroxychloroquine Drug Fails to Treat Acute Covid-19
- Hydroxychloroquine drug hyped by the US President Donald Trump for treating Covid-19 patients.
- This antimalarial drug recently evaluated in different clinical trials. Novartis and the University of Pennsylvania studied this drug.
- This malaria drug showed the capacity to potentially avert the replication of the SARS-CoV-2 virus in mammalian cells during laboratory studies.
- Columbia University researchers said that the data obtained from small human clinical studies were complex to unravel.
- The universities trial included about 1,400 patients with mild to acute Covid-19 illness at one New York hospital.
- In the latest trial out of 1,376 participants, 811 given hydroxychloroquine, and 565 patients not given the drug.
- The research is done to make sure that hydroxychloroquine use on the development of respiratory failure causing death or intubation.
- On the whole, 346 patients developed respiratory failure, 180 intubated and 166 died devoid of intubation.
- The result demonstrated that patients given hydroxychloroquine had the same risk of intubation or death as those who did not receive the drug.
- Thus, the researchers decided that hospitalized Covid-19 patients should not regularly be cured with hydroxychloroquine.
Pfizer, a US-based pharmaceutical company is working on four vaccine candidates along with BioNtech, its German Partner. They are developing RNA vaccine candidates. They have already started trials of BNT162. Inovio Pharmaceuticals, a Pennsylvania based biotech firm has developed a DNA Vaccine named INO-4800. The vaccine will so enter phase 1 Trials. Moderna a Massachusetts based biotech company is developing an RNA vaccine by partnering with the National Institute of Allergy and Infectious Diseases. The vaccine candidate mRNA-1273 has is all set to begin phase 2 trial after completing phase 1 trial.
The Serum Institute of India has too collaborated with Codagenix to create a credible vaccine. The vaccine will be ready to enter the market by 2022. Hyderabad based firm, Bharat Biotech has too joined hands to develop a unique vaccine for treating COVID-19 patients. It is an intranasal vaccine named CoroFlu and will be developed along with the University of Wisconsin & FluGen. Apart from all these, plasma treatment trials are on. But the results are not consistent and so ICMR has not yet declared it as a potential cure.
Indian Immunologicals Limited (IIL), a leading vaccines manufacturer has joined hands with Griffith University, Australia to research on a potential vaccine to fight the pandemic. Glenmark Pharmaceuticals has also started phase 3 clinical trials on the antiviral tablet named Favipiravir. The company has received approvals fro Drug Regulatory Body of India.
Australia set for Phase 1 Trial in COVID-19 vaccine
The Nucleus Network will start trials for their Coronavirus vaccine Novavax SARS-CoV-2 Recombinant Spike Protein Nanoparticle vaccine at various clinics in Melbourne & Brisbane. The trial is slated to begin in mid of May.
What Israel is up to it?
Israel has recently developed a COVID-19 vaccine which they claim that can neutralise the virus. Israel Institute for Biological Research has claimed to have zeroed on a monoclonal antibody which can kill Covid-19. Though its success on Humans is yet to be confirmed, still it is welcoming news for the World Community.
Italy has claimed to develop COVID-19 vaccine
Yes, it is true. One of the most affected countries due to this pandemic has revealed their success of developing a potential vaccine. Italian scientists made claims to develop a potential vaccine which generated antibodies in mice which can kill the virus in humans cells. The vaccine was tested in Spallanzani Hospital hospital in Rome and is said to have neutralized COVID-19 in human cells. More than 2 Lakh cases in the country, the development of a Coronavirus vaccine is good news.
Oxford Univerisity has started trials
Jenner Institute has seemed to develop a Coronavirus vaccine named ‘ChAdOx1 nCoV-19’. The vaccine is under phase 1 trial. The vaccine uses a weak strain of a common cold virus that causes infections in apes. To ensure the vaccine works, scientists have inserted the genetic material of the coronavirus present and is combined with the common cold virus.
What the Chinese are doing?
China too had its first coronavirus vaccine; Favilavir, which the Chinese Health Department approved. The drug has already shown results on 70 patients with minimum side effects. Further Trials are going on.
Almost a year will be needed to achieve Coronavirus treatment by developing potential vaccination. But with so many countries and health organizations participating in creating the vaccine, you can expect a weapon against this virus soon. A cure to this viral fever is lurking on the horizon, so stay indoors, eat healthily, exercise a lot, and stay fit!
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